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mouse mammary tumor virus polyoma virus middle t antigen  (Jackson Laboratory)

 
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    Structured Review

    Jackson Laboratory mouse mammary tumor virus polyoma virus middle t antigen
    Mouse Mammary Tumor Virus Polyoma Virus Middle T Antigen, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+mammary+tumor+virus/mice+mmtv+pymt/pmc12853815-60-0-14
    Average 86 stars, based on 1 article reviews
    mouse mammary tumor virus polyoma virus middle t antigen - by Bioz Stars, 2026-10
    86/100 stars

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    Related Articles

    Virus:

    Article Title: Of mice, cats, and men: is human breast cancer a zoonosis?
    Article Snippet: Mouse mammary tumor virus (MMTV), a member of the betaretroviridae, is the most common cause of breast cancer (BC) in mice.. MMTV is transmitted in mice both in the germline as endogenous proviruses and exogenously as infectious virions.. Here, we review a variety of evidence accumulated for six decades that has suggested that a human homologue of MMTV may exist.

    Article Title: Mus tales: a hands-on view.
    Article Snippet: The mouse model for breast cancer has developed into a most effective means of dissecting and understanding this devastating disease.. The inbred transgenic mouse lends itself to biological, molecular, immunological, and genetic studies.. The observation, dissection, transplantation, and subsequent amplification of precancerous mammary lesions and tumors give the scientist the means to readily study the tissues and design interventions and therapeutic drugs for the future eventual control of breast cancer.

    Article Title: Assays for Anti-Cancer Screening of Medical Plants: A Review
    Article Snippet: .. • Mouse Mammary Tumor Virus (MMTV) was the first mouse virus, isolated at Jackson Lab as the “nonchromosomal factor” that caused mammary tumours in C3H strain of mice. ..

    Article Title: Genetic Control of Ductal Morphology, Estrogen-Induced Ductal Growth, and Gene Expression in Female Mouse Mammary Gland
    Article Snippet: .. In addition, many of the reports investigating the genetic control of the mammary response to E 2 were prior to 1999 ( 12 , 14 , 19 ), when mouse mammary tumor virus (MMTV) was eradicated from inbred mice (The Jackson Laboratory, personal communication). ..

    Article Title: Sequences within the gag Gene of Mouse Mammary Tumor Virus Needed for Mammary Gland Cell Transformation
    Article Snippet: .. Sequences within the gag Gene of Mouse Mammary Tumor Virus Needed for Mammary Gland Cell Transformation Ingrid Swanson, Brooke A. Jude, Annie R. Zhang, Andrew Pucker,† Zachary E. Smith, and Tatyana V. Golovkina* The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609 Received 4 September 2005/Accepted 10 January 2006 Previously, we identified a group of replication-competent exogenous mouse mammary tumor viruses that failed to induce mammary tumors in susceptible mice. ..

    Article Title: A Compendium of the Mouse Mammary Tumor Biologist: From the Initial Observations in the House Mouse to the Development of Genetically Engineered Mice
    Article Snippet: .. The discovery and verification of the extrachromosomal “milk agent” at the Jackson Laboratory and in the Netherlands heralded a new epoch featuring the “cause” of familial breast cancer, namely the mouse mammary tumor virus (MMTV) ( Laboratory S. o. RBJM 1933 ). ..

    Isolation:

    Article Title: Assays for Anti-Cancer Screening of Medical Plants: A Review
    Article Snippet: .. • Mouse Mammary Tumor Virus (MMTV) was the first mouse virus, isolated at Jackson Lab as the “nonchromosomal factor” that caused mammary tumours in C3H strain of mice. ..

    Control:

    Article Title: Genetic Control of Ductal Morphology, Estrogen-Induced Ductal Growth, and Gene Expression in Female Mouse Mammary Gland
    Article Snippet: .. In addition, many of the reports investigating the genetic control of the mammary response to E 2 were prior to 1999 ( 12 , 14 , 19 ), when mouse mammary tumor virus (MMTV) was eradicated from inbred mice (The Jackson Laboratory, personal communication). ..

    Transformation Assay:

    Article Title: Sequences within the gag Gene of Mouse Mammary Tumor Virus Needed for Mammary Gland Cell Transformation
    Article Snippet: .. Sequences within the gag Gene of Mouse Mammary Tumor Virus Needed for Mammary Gland Cell Transformation Ingrid Swanson, Brooke A. Jude, Annie R. Zhang, Andrew Pucker,† Zachary E. Smith, and Tatyana V. Golovkina* The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609 Received 4 September 2005/Accepted 10 January 2006 Previously, we identified a group of replication-competent exogenous mouse mammary tumor viruses that failed to induce mammary tumors in susceptible mice. ..



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    Image Search Results


    Schematic representation of (a) proviral genome organization across retroviral genera, and (b) a mature retroviral particle showing a dimeric genome inside the core. Representative viruses include: ALV, avian leukosis virus; MMTV, mouse mammary tumor virus; MLV, murine leukemia virus; HTLV-1, human T-lymphotropic virus type 1; WDSV, Walleye dermal sarcoma virus; HIV-1, human immunodeficiency virus type 1; and SFV, simian foamy virus. Black vertical arrows indicate the sites of ribosomal frameshifting within each proviral genome. nts: Nucleotides. Figure made in BioRender.com .

    Journal: FEMS Microbiology Reviews

    Article Title: Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication

    doi: 10.1093/femsre/fuaf066

    Figure Lengend Snippet: Schematic representation of (a) proviral genome organization across retroviral genera, and (b) a mature retroviral particle showing a dimeric genome inside the core. Representative viruses include: ALV, avian leukosis virus; MMTV, mouse mammary tumor virus; MLV, murine leukemia virus; HTLV-1, human T-lymphotropic virus type 1; WDSV, Walleye dermal sarcoma virus; HIV-1, human immunodeficiency virus type 1; and SFV, simian foamy virus. Black vertical arrows indicate the sites of ribosomal frameshifting within each proviral genome. nts: Nucleotides. Figure made in BioRender.com .

    Article Snippet: Some retroviruses are responsible for causing immunodeficiency in humans and animals, such as human, feline, simian, and bovine immunodeficiency viruses (HIV, FIV, SIV, and BIV) and Mason–Pfizer monkey virus (MPMV); neoplastic diseases caused by Rous sarcoma virus (RSV), avian leukosis virus (ALV), human T-lymphotropic virus type 1 (HTLV-1), murine, feline, and bovine leukemia viruses (MLV, FLV, and BLV), and mouse mammary tumor virus (MMTV; Goff , Skalka ).

    Techniques: Retroviral, Virus

    Illustration of the mechanisms used by different retroviruses for the nuclear export of their full-length unspliced RNA. HIV-1, human immunodeficiency virus type 1; HTLV-1, human T-lymphotropic virus type 1; MMTV, mouse mammary tumor virus; CRM1, chromosome region maintenance 1 protein; MPMV, Mason–Pfizer monkey virus; MLV, murine leukemia virus; CTE, constitutive transport element; CAE, cytoplasmic accumulation element; NXF1/TAP, nuclear RNA export factor 1; and HuR, human antigen R. See text for details. Figure made in BioRender.com .

    Journal: FEMS Microbiology Reviews

    Article Title: Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication

    doi: 10.1093/femsre/fuaf066

    Figure Lengend Snippet: Illustration of the mechanisms used by different retroviruses for the nuclear export of their full-length unspliced RNA. HIV-1, human immunodeficiency virus type 1; HTLV-1, human T-lymphotropic virus type 1; MMTV, mouse mammary tumor virus; CRM1, chromosome region maintenance 1 protein; MPMV, Mason–Pfizer monkey virus; MLV, murine leukemia virus; CTE, constitutive transport element; CAE, cytoplasmic accumulation element; NXF1/TAP, nuclear RNA export factor 1; and HuR, human antigen R. See text for details. Figure made in BioRender.com .

    Article Snippet: Some retroviruses are responsible for causing immunodeficiency in humans and animals, such as human, feline, simian, and bovine immunodeficiency viruses (HIV, FIV, SIV, and BIV) and Mason–Pfizer monkey virus (MPMV); neoplastic diseases caused by Rous sarcoma virus (RSV), avian leukosis virus (ALV), human T-lymphotropic virus type 1 (HTLV-1), murine, feline, and bovine leukemia viruses (MLV, FLV, and BLV), and mouse mammary tumor virus (MMTV; Goff , Skalka ).

    Techniques: Virus

    Illustration of the Gag domain organization in different retroviruses that include MA, CA, and NC. Spacer peptides (SP), other peptides (p or pp followed by a number), and late (L) domain-containing sequences are also shown. HIV/FIV/SIV, human, feline, and simian immunodeficiency viruses; MLV, murine leukemia virus; MMTV, mouse mammary tumor virus; and MPMV, Mason–Pfizer monkey virus. The L domain amino acids are as follows: PTAP: Pro-Thr-Ala-Pro; YPXnL (Tyr-Pro-any amino acid and n = ∼ 1–3 residues-Leu); PSAP: Pro-Ser-Ala-Pro; LXXL: Leu-any amino acid-any amino acid-Leu; PPxY: Pro-Pro-any amino acid-Tyr; and PLPPV: Pro-Leu-Pro-Pro-Val. Figure made in BioRender.com .

    Journal: FEMS Microbiology Reviews

    Article Title: Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication

    doi: 10.1093/femsre/fuaf066

    Figure Lengend Snippet: Illustration of the Gag domain organization in different retroviruses that include MA, CA, and NC. Spacer peptides (SP), other peptides (p or pp followed by a number), and late (L) domain-containing sequences are also shown. HIV/FIV/SIV, human, feline, and simian immunodeficiency viruses; MLV, murine leukemia virus; MMTV, mouse mammary tumor virus; and MPMV, Mason–Pfizer monkey virus. The L domain amino acids are as follows: PTAP: Pro-Thr-Ala-Pro; YPXnL (Tyr-Pro-any amino acid and n = ∼ 1–3 residues-Leu); PSAP: Pro-Ser-Ala-Pro; LXXL: Leu-any amino acid-any amino acid-Leu; PPxY: Pro-Pro-any amino acid-Tyr; and PLPPV: Pro-Leu-Pro-Pro-Val. Figure made in BioRender.com .

    Article Snippet: Some retroviruses are responsible for causing immunodeficiency in humans and animals, such as human, feline, simian, and bovine immunodeficiency viruses (HIV, FIV, SIV, and BIV) and Mason–Pfizer monkey virus (MPMV); neoplastic diseases caused by Rous sarcoma virus (RSV), avian leukosis virus (ALV), human T-lymphotropic virus type 1 (HTLV-1), murine, feline, and bovine leukemia viruses (MLV, FLV, and BLV), and mouse mammary tumor virus (MMTV; Goff , Skalka ).

    Techniques: Virus